Bioengineered Organs Initiative Researcher
Cook Cardiopulmonary Engineering Group, Carnegie Mellon University
Pittsburgh, Pennsylvania · September 2021 - September 2023
- Conducted two years of graduate biomedical engineering research developing and experimentally evaluating a temporary liver-support prototype for ammonia removal in acute liver failure.
- Designed, fabricated, assembled, instrumented, and tested the experimental system, including custom parts, vacuum-pressure operation, PDMSA flexible silicone-based polymer often used to make membranes, seals, and microfluidic devices. membrane, perfluorocarbonA fluorinated liquid used here as part of the ammonia-removal system., and simulated peritoneal-fluid experiments.
- Measured and analyzed gas ammonia, liquid ammonium, pH, temperature, pressure, mass, and volumetric flow; investigated calibration drift, uncertainty, anomalous measurements, and reference comparisons.
- Developed custom Arduino C and MATLAB workflows, including a MATLAB analysis program of more than 3,300 lines for organizing, synchronizing, statistically analyzing, and reporting multi-device experimental data.
- Authored an M.S. thesis and a 177-page companion data-analysis report.
- Presented research repeatedly to Cook Lab colleagues and Mayo Clinic collaborators, including 24 lab-meeting updates, 6 long-form presentations, and 6 presentations to Mayo Clinic physicians and staff.
- Developed and implemented BSL-2 laboratory safety procedures for ammonia-related work, coordinating with Environmental Health & Safety and equipment vendors and using fume hoods, gas monitoring, fit-tested full-face respiratory protection, and emergency procedures.